Comparison

MDC Recombinant Protein

Item no. PRS-40-387-0.005mg
Manufacturer ProSci
Amount 0.005 mg
Category
Type Proteins Recombinant
Format Lyophilized
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias MDC, ABCD-1, SCYA22, STCP-1, DC/B-CK, A-152E5.1, MDC, C-C motif chemokine 22, CC chemokine STCP-1
Available
Storage Conditions
The lyophilized MDC recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted MDC is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing MDC recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Disclaimer
This product is for research use only.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μ g (1EU/μ g).
Background
MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Accession #
NP_002981.2
Ncbi Gene Id #
6367
Ncbi Official Symbol
CCL22
Ncbi Official Full Name
chemokine (C-C motif) ligand 22
Ncbi Organism
Homo sapiens
Swissprot #
O00626
Sequence
YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ
Biological Activity
Biological activity was determined by its ability to chemoattract human T cells using a concentration range of 10.0 - 100.0 ng/mL.
Protein Gi#
22538804
Peptide Sequence
YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.005 mg
Available: In stock
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