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SARS-CoV-2 (COVID-19) S Recombinant Protein RBD

SARS-CoV-2 (COVID-19) S Recombinant Protein RBD

Item no.	PRS-11-215-0.2mg
Manufacturer	ProSci
Amount	0.2 mg
Category	Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Recombinant Proteins Western Blot ELISA
Type	Proteins Recombinant
Format	Liquid
Applications	WB, ELISA
Specific against	other
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19
Available
Applications	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Applications	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Buffer	10 mM PB, pH7.4
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	27.0 kDa
Purity	>95% as determined by SDS-PAGE.
Background	It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
1St Image Caption3	SARS-CoV-2 S protein RBD, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Background References 1	Wan Y, et al. J Virol. 2020. pii: JVI.00127-20.
Background References 2	Benvenuto D, et al. J Med Virol. 2020.
Background References 3	Chang CY, et al. AMB Express. 2020. 10(1):20.
Accession #	QHD43416.1
Ncbi Gene Id #	43740568
Ncbi Official Symbol	S
Ncbi Official Full Name	surface glycoprotein
Ncbi Organism	Homo sapiens
Swissprot #	P0DTC2
Fusion Tag	His Tag
Sequence	N/A

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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