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HCoV-OC43 Nucleocapsid protein, His Tag

HCoV-OC43 Nucleocapsid protein, His Tag

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Coronavirus
Format	Powder
Amount	1 mg
Host	E.coli
Item no.	NUN-V5145-1mg
Conjugate/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	Nucleocapsid protein,NP,Protein N,COVID-19
Purity	90%
Manufacturers Category	Protein / Viral Proteins
Description	HCoV-OC43 Nucleocapsid, His Tag (NUN-V5145) is expressed from E. coli cells. It contains AA Met 1 - Ile 448 (Accession # P33469-1).
Molecule	Nucleocapsid protein
Exp Region	Met 1 - Ile 448
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	50.3 kDa
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	40 mM PB, 500 mM NaCl, pH7.4
Background	Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.