[Novoprotein] Recombinant E. coli Malate Dehydrogenase/MDH (N-6His)

Escherichia coli MDH, also known as Malate dehydrogenase, is a group of multimeric enzymes consisting of identical subunits usually organized as either dimer or tetramers with subunit molecular weights of 30-35 kDa. Its major function is to catalyze the NAD / NADH-dependent interconversion of the substrates malate & oxaloacetate. This reaction plays a key part in the malate / aspartate shuttle across the mitochondrial membrane, & in the tricarboxylic acid cycle within the mitochondrial matrix.MDH is synthesized in several organisms including archaea, eubacteria, fungi, plant & mammals. The enzymes share a common catalytic mechanism & their kinetic properties are similar, which demonstrates a high degree of structural similarity. The three-dimensional structures & elements essential for catalysis are conserved between mitochondrial & cytoplasmic forms of MDH in eukaryotic cells even though these isoenzymes are only marginally related at the level of primary structure.

Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

34, 6

Met1-Lys312

Store at < -20C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.