Item no. |
NKM-LAR3001-0.5mg |
Manufacturer |
NKMAX
|
Amount |
0.5mg |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Conjugate/Tag |
Non-Tagged |
Purity |
> 95% by SDS - PAGE |
Sequence |
MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG |
NCBI |
NP_002278 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Leukocyte-associated immunoglobulin-like receptor 1 isoform a, Lair1, LAIR-1 (Extracellular domain), LAIR-1, mLAIR1, CD305 antigen, Leukocyte-associated immunoglobulin-like receptor 1, Leukocyte-associated immunoglobulin-like receptor 1 isoform a 5133400O11Rik, CD305, D7Bwg0421e, LAIR 1, LAIR1 protein, Leukocyte associated Ig like receptor 1, Leukocyte associated immunoglobulin like receptor 1, |
Available |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1 mg/ml (determined by Bradford assay) |
Description |
LAIR-1 is a glycoprotein (ca.32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1 ( 22-125aa) was overexpressed in E. coli, and purified by using conventional chromatography techniques. |
Domain |
22-125aa |
Expression System |
E.coli |
Formulation |
Liquid. In 20 mM Tris-HCl (pH7.5) 50mM NaCl, 1mM EDTA |
Gene Category |
Immunology |
General References |
Sathish JG., et al. (2001) J Immunol. 166(3):1763-70. Meyaard L., et al. (1999) J. Immunol. 162, 5800-4. |
Molecular Weight |
11.7 kDa (105 aa), confirmed by MALDI-TOF. |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.