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Recombinant e.coli Dnak protein

Recombinant e.coli Dnak protein

Item no.	NKM-DNK3004-20ug
Manufacturer	NKMAX
Amount	20ug
Category	Oncology Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	Non-Tagged
Purity	> 95% by SDS-PAGE
NCBI	NP_414555
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Dnak (508-638), A lid covering the substrate, Heat shock protein 70, Heat shock 70 kDa protein, HSP70, Chaperone protein dnaK, Chaperone Hsp 70, Co chaperone with DnaJ, dnaK, Heat shock 70 kDa protein,
Available
Antigen Species	E.coli
Bioassay Procedure	MNEDEIQKMV RDAEANAEAD RKFEELVQTR NQGDHLLHST RKQVEEAGDK LPADDKTAIE SALTALETAL KGEDKAAIEA KMQELAQVSQ KLMEIAQQQH AQQQTAGADA SANNAKDDDV VDAEFEEVKD KK
Concentration	1mg/ml (determined by BCA assay)
Description	DnaK, originally identified for its DNA replication by bacteriophage lambda in E. coli is the bacterial hsp70 chaperone. This protein is involved in the folding and assembly of newly synthesized polypeptide chains and in preventing the aggregation of stress-denatured proteins. Dnak (residues 508-638) of the substrate binding domain is alpha-helical and appears to act as a lid covering the substrate binding cleft. DnaK (amino acid 508-638) was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques. Additional amino acid (Met) is attached at N- terminus
Domain	508-638aa
Expression System	E.coli
Formulation	Liquid in. 25mM Tris-HCl buffer (pH 7.5) containing 100mM NaCl, 10% glycerol
Gene Category	Heat Shock Proteins
General References	Bardwell & Craig (1984) Proc. Natl. Acad. Sci. 81, 848-852; ; Zhu et al., (1996) Science 272, 1606-1614.; ; Naoki tanaka., et al (2002) PNAS 26(99)15398-15403; ;
Molecular Weight	14.6 kDa (132aa)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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