Item no. |
NKM-BLS0801-100ug |
Manufacturer |
NKMAX
|
Amount |
100ug |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Conjugate/Tag |
His-Tag |
Purity |
> 95% by SDS - PAGE |
Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAV QGPEETVTQD CLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL |
NCBI |
NP_006564 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
B lymphocyte stimulator, B-cell activating factor, BAFF, CD257, TALL1, THANK, ZTNF4, TNFSF13B, TNFSF20, BlyS, B lymphocyte stimulator, B lymphocyte stimulator |
Available |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1 mg/ml (determined by Bradford assay) |
Description |
B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor (TNF) superfamily of cytokines, induces B-cell proliferation and immunoglobulin secretion and is a key regulator of peripheral B-cell populations in vivo.. BLyS is made by immune-cells called monocytes and macrophages. When monocytes and macrophages are activated, BLyS is released and binds to a receptor found only on B cells. Recombinant human BLyS, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
Domain |
134-285aa |
Endotoxin |
< 1.0 EU per 1ug of protein (determined by LAL method) |
Expression System |
E.coli |
Formulation |
Liquid in 20mM Tris pH 8.0, 5mM DTT |
Gene Category |
Hormones & Cytokines |
General References |
Allan SM., et al. (2005), Nat. Rev. Immunol. 5:629. Michaud DS., et al. (2006), Cancer Res. 66(8):4525-30 |
Molecular Weight |
21 kDa (190 aa) |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.