Item no. |
NKM-ATGP3984-20ug |
Manufacturer |
NKMAX
|
Amount |
20ug |
Category |
|
Type |
Proteins Recombinant |
Applications |
SDS-PAGE |
Specific against |
other |
Conjugate/Tag |
His-Tag |
Purity |
> 95% by SDS - PAGE |
NCBI |
NP_742115.2 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
ectonucleoside triphosphate diphosphohydrolase 6 isoform1, 2700026H11Rik, Cd39l, Cd39l2, dJ738P15.3, NTPDa, NTPDase-6, Entpd6 |
Available |
|
Antigen Species |
Mouse |
Bioactivity Comment Only |
Specific activity is > 80, 000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze GDP per minute at pH 7.5 at 25C. |
Bioactivity Comment and Pics |
Specific activity is > 80, 000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze GDP per minute at pH 7.5 at 25C. |
Bioassay Procedure |
KWHRAS AAQAFFTIAG AASGARWTQQ AFSSPGSAAR GHEVFYGIMF DAGSTGTRIH VFQFARPPGE TPTLTHETFK ALKPGLSAYA DDVEKSAQGI QELLNVAKQH IPYDFWKATP LVLKATAGLR LLPGEKAQKL LQKVKEVFKA SPFLVGDDCV SIMNGTDEGV SAWITVNFLT GSLKTPGSSS VGMLDLGGGS TQITFLPRVE GTLQASPPGH LTALQMFNRT YKLYSYSYLG LGLMSARLAI LGGVEGKPAE NDKELVSPCL SPRFRGEWEH AEVTYRISGQ KAVGLYELCA SRVSEVLRNK VHRTEEAQHV DFYAFSYYYD LAASFGLIDA EKGGSLVVGD FEIAAKYVCR TLETQPPSSP FACMDLTYIS LLLHEFGFPG DKVLKLARKI DNVETSWALG AIFHYIDSLK RQKVPAL |
Concentration |
0.25mg/ml (determined by Absorbance at 280nm) |
Description |
CD39L2, also known as ENTPD6, is a nucleoside phosphohydrolase of the CD39 family of enzymes that is present on the surface of cells. It is soluble monomeric enzyme, making it more amenable to thorough structural and fuctional analysis than the membrane-bound forms. Soluble CD39L2 preferentially exhibits nucleoside diphosphatase activity, which is depedent on the presence of divalent cations. It is expressed at its highest levels in cardiac muscle and in heart capillary endothelial cells. Also, it plays a role in the regulation and recruitment of platelet activation in heart. Recombinant mouse CD39L2, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
Domain |
33-455aa |
Endotoxin |
< 1 EU per 1ug of protein (determined by LAL method) |
Expression System |
HEK293 |
Formulation |
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol |
Gene Category |
Signal Transduction, Metabolism |
General References |
Yeung G., et al, (2000) Biochemistry. 39:12916-12923.; ; Hicks-Berger CA, et al, (2000) J Biol Chem. 275:34041-34045.; ; Ivanenkov VV, et al, (2003) Biochemistry. 42:11726-11735.; ; |
Molecular Weight |
47.3kDa (433aa) |
Predicted nterm |
Asp |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.