Item no. |
NKM-ATGP3971-500ug |
Manufacturer |
NKMAX
|
Amount |
500ug |
Category |
|
Type |
Proteins Recombinant |
Applications |
SDS-PAGE |
Specific against |
other |
Conjugate/Tag |
hIgG-His-Tag |
Purity |
> 95% by SDS - PAGE |
NCBI |
NP_035789.1 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Tumor necrosis factor receptor superfamily member 4, OX40 antigen, OX40L receptor, CD134, Txgp1, Tnfrsf4, tax-transcriptionally activated glycoprotein 1, TXGP1L, ACT35, Ly-70, ACT3, OX4, Txgp |
Available |
|
Antigen Species |
Mouse |
Bioassay Procedure |
VTARRL NCVKHTYPSG HKCCRECQPG HGMVSRCDHT RDTLCHPCET GFYNEAVNYD TCKQCTQCNH RSGSELKQNC TPTQDTVCRC RPGTQPRQDS GYKLGVDCVP CPPGHFSPGN NQACKPWTNC TLSGKQTRHP ASDSLDAVCE DRSLLATLLW ETQRPTFRPT TVQSTTVWPR TSELPSPPTL VTPEGP |
Concentration |
0.25mg/ml (determined by Absorbance at 280nm) |
Description |
TNFRSF4, also known as CD134, is a member of the TNFR-superfamily of receptors. It is a receptor for TNFSF4/OX40L/GP34. This protein is a costimulatory molecule implicated in long-term T-cell immunity. The interaction with OX40L regulates antigen-specific T-cell expansion and survival, cytokine production. It also modulates cytokine receptor signalling. Therefore the interaction between TNFRSF4 and CD40L plays a key role in the development of multiple imflammatry and autoimmune disease. Recombinant mouse OX40/TNFRSF4 , fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
Domain |
20-211aa |
Endotoxin |
< 1 EU per 1ug of protein (determined by LAL method) |
Expression System |
HEK293 |
Formulation |
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
General References |
Schreiber TH, et al, (2012) J Immunol. 189:3311-3318.; Webb GJ, et al, (2016) Clin Rev Allergy Immunol. 50:312-332.; Zhou B, et al, (2020) Transplant Proc. 52:398-405.; |
Molecular Weight |
48.7kDa (435aa) |
Predicted nterm |
Asp |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.