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Recombinant human IL-17 RA/IL-17 R protein

Recombinant human IL-17 RA/IL-17 R protein

Item no.	NKM-ATGP3632-4ug
Manufacturer	NKMAX
Amount	4ug
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines SDS-PAGE
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	hIgG-His-Tag
Purity	> 90% by SDS-PAGE
NCBI	NP_055154
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-17 receptor A isoform 1, IL17RA, CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R, IMD51
Available
Antigen Species	Human
Bioassay Procedure	LRLLDHRALV CSQPGLNCTV KNSTCLDDSW IHPRNLTPSS PKDLQIQLHF AHTQQGDLFP VAHIEWTLQT DASILYLEGA ELSVLQLNTN ERLCVRFEFL SKLRHHHRRW RFTFSHFVVD PDQEYEVTVH HLPKPIPDGD PNHQSKNFLV PDCEHARMKV TTPCMSSGSL WDPNITVETL EAHQLRVSFT LWNESTHYQI LLTSFPHMEN HSCFEHMHHI PAPRPEEFHQ RSNVTLTLRN LKGCCRHQVQ IQPFFSSCLN DCLRHSATVS CPEMPDTPEP IPDYMPLW
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Description	IL17RA, also known as interleukin-17 receptor A isoform 1, is a cytokine receptor which binds interleukin 17. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. It is a type1 membrane glycoprotein that binds with low affinity to interleukin 17A. This protein and Interleukin 17A play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Recombinant human IL17RA, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Domain	33-320aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Expression System	Baculovirus
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Gene Category	Immunology
General References	Honorati MC., et al, (2001) Rheumatology 40:522-527.; ; Yao Z., et al, (1997) Cytokine 9:794-800.
Molecular Weight	60.4 kDa (527aa)
Predicted nterm	Leu33

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 4ug

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Delivery expected until 10/4/2024

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