Item no. |
NKM-ATGP3450-500ug |
Manufacturer |
NKMAX
|
Amount |
500ug |
Category |
|
Type |
Proteins |
Applications |
SDS-PAGE |
Specific against |
other |
Conjugate/Tag |
His-Tag |
Purity |
> 90% by SDS-PAGE |
NCBI |
NP_034638.2 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Interferon alpha/beta receptor 1, Ifnar1, CD118, Ifar, Ifnar, Ifrc, Infar |
Available |
|
Antigen Species |
Mouse |
Bioassay Procedure |
ENLKPPENID VYIIDDNYTL KWSSHGESMG SVTFSAEYRT KDEAKWLKVP ECQHTTTTKC EFSLLDTNVY IKTQFRVRAE EGNSTSSWNE VDPFIPFYTA HMSPPEVRLE AEDKAILVHI SPPGQDGNMW ALEKPSFSYT IRIWQKSSSD KKTINSTYYV EKIPELLPET TYCLEVKAIH PSLKKHSNYS TVQCISTTVA NKMPVPGNLQ VDAQGKSYVL KWDYIASADV LFRAQWLPGY SKSSSGSRSD KWKPIPTCAN VQTTHCVFSQ DTVYTGTFFL HVQASEGNHT SFWSEEKFID SQKHILPPPP VITVTAMSDT LLVYVNCQDS TCDGLNYEII FWENTSNTKI SMEKDGPEFT LKNLQPLTVY CVQARVLFRA LLNKTSNFSE KLCEKTRPGS FST |
Concentration |
0.5mg/ml (determined by absorbance at 280nm) |
Description |
Ifnar1, also known as Interferon alpha/beta receptor 1, is a member of the class II cytokine receptor family of proteins. This protein forms one of the two chains of a receptor for interferons alpha and beta. It binds and activate of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Recombinant mouse Ifnar1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Domain |
27-429aa |
Endotoxin |
< 1 EU per 1ug of protein (determined by LAL method) |
Expression System |
Baculovirus |
Formulation |
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Category |
Immunology |
General References |
Langer JA., et al. (2004) Cytokine Growth Factor Rev. 15:33-48.; ; Yan H., et al. (1996) EMBO J. 15:1064-1074. |
Molecular Weight |
46.8 kDa (411aa) |
Predicted nterm |
Glu27 |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.