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Recombinant human S100A8 protein

Recombinant human S100A8 protein

Item no.	NKM-ATGP3372-500ug
Manufacturer	NKMAX
Amount	500ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Targets for Rodent Neurosciences By Cell Type Melanoma Peptides & Proteins Recombinant Proteins SDS-PAGE Cytoskeleton Markers
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	His-Myc-Tag
Purity	> 90% by SDS-PAGE
NCBI	NP_002955
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8
Available
Antigen Species	Human
Concentration	1mg/ml (determined by Bradford assay)
Description	S100A8, also known as S100A8 isoform d. S100A8 is a member of the S100 family, EF-hand superfamily of Calcium binding proteins. S100A8 protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant human S100A8, fused to His-tag at N-terminus, fused to Myc-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Expression System	E.coli
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Gene Category	Cancer
General References	Kerkhoff C., et al. (1998) Biochim. Biophys. 1448(2):200-11. ; ; Nacken W., et al. (2003) Microsc Res Tech. 60(6):569-80.
Molecular Weight	14.5 kDa (127aa) confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500ug

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Delivery expected until 10/4/2024

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