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Recombinant human IL-38/IL-1F10 protein

Recombinant human IL-38/IL-1F10 protein

Item no.	NKM-ATGP3044-20ug
Manufacturer	NKMAX
Amount	20ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	Non-Tagged
Purity	> 95% by SDS-PAGE
NCBI	NP_115945
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL38, Interleukin-1 family member 10, Interleukin-1 family member 10, FIL1-theta, FKSG75, IL1HY2, IL-38, IL1-theta, IL1HY2
Available
Antigen Species	Human
Bioassay Procedure	MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW
Concentration	1mg/ml (determined by Bradford assay)
Description	IL1F10 also known as interleukin-1 family member 10. IL1F10 is cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. It reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. It increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS) and ligand for IL-36R/IL1RL2. Recombinant human IL1F10 was expressed in E. coli and purified by using conventional chromatography techniques
Domain	1-152aa
Expression System	E.coli
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4)
Gene Category	Immunology
General References	Bensen J.T., et al. (2001) J. Interferon Cytokine Res. 21:899-904.; ; van de Veerdonk F.L., et al. (2012) Proc. Natl. Acad. Sci. u.S.A. 109:3001-3005.; ;
Molecular Weight	16.9 kDa (152aa) confirmed by MALDI-TOF

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20ug

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Delivery expected until 10/4/2024

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