Item no. |
NKM-ATGP2453-0.5mg |
Manufacturer |
NKMAX
|
Amount |
0.5mg |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Conjugate/Tag |
His-Tag |
Purity |
> 90% by SDS - PAGE |
Sequence |
MGSSHHHHHH SSGLVPRGSH MGSYSGEKKC WNRSGHCRKQ CKDGEAVKDT CKNLRACCIP SNEDHRRVPA TSPTPLSDST PGIIDDILTV RFTTDYFEVS SKKDMVEESE AGRGTETSLP NVHHSS |
NCBI |
NP_473453 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Beta-defensin 118 precursor, C20orf63; DEFB-18; ESC42, ESP13.6 |
Available |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
0.5 mg/ml (determined by Bradford assay) |
Description |
DEFB118 is a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This protein is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Recombinant human DEFB118 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
Domain |
21-123aa |
Expression System |
E.coli |
Formulation |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT |
Gene Category |
Immunology |
General References |
Kao CY, Chen Y, et al. (2003). Am J Respir Cell Mol Biol. 29(1):71-80. Schutte BC, Mitros JP, et al. (2002). Proc Natl Acad Sci u S A. 99(4):2129-33. |
Molecular Weight |
13.8kDa (126aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.