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Recombinant human AP1AR protein

Recombinant human AP1AR protein

Item no.	NKM-ATGP2321-4ug
Manufacturer	NKMAX
Amount	4ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 90% by SDS-PAGE
NCBI	NP_061039
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Adaptor-related protein complex 1 associated regulatory protein, Adaptor-related protein complex 1 associated regulatory protein, 2C18, C4orf16, gamma-BAR, GBAR, PRO0971
Available
Antigen Species	Human
Bioassay Procedure	MGSSHHHHHH SSGLVPRGSH MGNCCWTQCF GLLRKEAGRL QRVGGGGGSK YFRTCSRGEH LTIEFENLVE SDEGESPGSS HRPLTEEEIV DLRERHYDSI AEKQKDLDKK IQKELALQEE KLRLEEEALY AAQREAARAA KQRKLLEQER QRIVQQYHPS NNGEYQSSGP EDDFESCLRN MKSQYEVFRS SRLSSDATVL TPNTESSCDL MTKTKSTSGN DDSTSLDLEW EDEEGMNRML PMRERSKTEE DILRAALKYS NKKTGSNPTS ASDDSNGLEW ENDFVSAEMD DNGNSEYSGF VNPVLELSDS GIRHSDTDQQ TR
Concentration	0.25mg/ml (determined by Bradford assay)
Description	Adaptor-related protein complex 1 associated regulatory protein, also known as AP1AR, is necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. This protein regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Recombinant human AP1AR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Domain	1-302aa
Expression System	E.coli
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Gene Category	Signal Transduction
General References	Neubrand V.E., et al. (2005) EMBO J. 24:1122-1133; ; Wollscheid B., et al. (2009) Nat. Biotechnol. 27:378-386; ;
Molecular Weight	36.4 kDa (322aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 4ug

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Delivery expected until 10/4/2024

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