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Recombinant human Carboxypeptidase E/CPE protein

Recombinant human Carboxypeptidase E/CPE protein

Item no.	NKM-ATGP1953-0.5mg
Manufacturer	NKMAX
Amount	0.5mg
Category	Metabolism Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity
Type	Proteins Recombinant
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 85% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MGSLQQEDGI SFEYHRYPEL REALVSVWLQ CTAISRIYTV GRSFEGRELL VIELSDNPGV HEPGEPEFKY IGNMHGNEAV GRELLIFLAQ YLCNEYQKGN ETIVNLIHST RIHIMPSLNP DGFEKAASQP GELKDWFVGR SNAQGIDLNR NFPDLDRIVY VNEKEGGPNN HLLKNMKKIV DQNTKLAPET KAVIHWIMDI PFVLSANLHG GD
NCBI	NP_001864
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Carboxypeptidase E, Carboxypeptidase H, CPH
Available
Antigen Species	Human
Applications info	SDS-PAGE
Concentration	0.5 mg/ml (determined by Bradford assay)
Description	CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but constitutively secreted proteins. Mutations in CPE are implicated in type II diabetes. Recombinant human CPE protein, fused to His-tag at N-terminus, was expressed in E. coli.
Domain	43-476aa
Expression System	E.coli
Formulation	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Gene Category	Metabolism
General References	Chu, K.Y., et al. (2011) Islets 3 (4), 155-165 Lee, T.K., et al. (2011) J. Clin. Invest. 121 (3), 880-892
Molecular Weight	51.4 kDa (457aa)
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 10/4/2024

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