Item no. |
NKM-ATGP1790-500ug |
Manufacturer |
NKMAX
|
Amount |
500ug |
Category |
|
Type |
Proteins Recombinant |
Applications |
SDS-PAGE |
Specific against |
other |
Conjugate/Tag |
His-Tag |
Purity |
> 85% by SDS-PAGE |
NCBI |
NP_001035533 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
PHF11, PHD finger protein 11, APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34, RP11-185C18.3 |
Available |
|
Antigen Species |
Human |
Concentration |
1mg/ml (determined by Bradford assay) |
Description |
PHD finger protein 11, also known as PHF11, is a regulator of TH1-type cytokine gene expression. The reduction in PHF11 expression seen with an AD-associated genotype could contribute to the strong TH2 responses that characterize many allergic individuals. PHF11 are associated with increased total serum IgE levels, asthma, and severe atopic dermatitis (AD) in children. Although PHF11 includes a plant homeodomain, a motif often found in transcriptional regulators, the function of PHF11 has not been investigated. Recombinant human PHF11 protein, fused to His-tag at N-terminus, was expressed in E. coli. |
Expression System |
E.coli |
Formulation |
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Gene Category |
Epigenomics (Transcription & Translation) |
General References |
Clarke E., et al. (2008) J. Allergy Clin. Immunol. 121:1148-1154; ; Scanlan M.J., et al. (1999) Int. J. Cancer. 83:456-464; ; |
Molecular Weight |
39.7 kDa (351aa) |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.