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Recombinant human PHF11 protein

Recombinant human PHF11 protein

Item no.	NKM-ATGP1790-0.5mg
Manufacturer	NKMAX
Amount	0.5mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 85% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MAQASPPRPE RVLGASSPEA RPAQEALLLP TGVFQVAEKM EKRTCALCPK DVEYNVLYFA QSENIAAHEN CLLYSSGLVE CEDQDPLNPD RSFDVESVKK EIQRGRKLKC KFCHKRGATV GCDLKNCNKN YHFFCAKKDD AVPQSDGVRG IYKLLCQQHA QFPIIAQSAK FSGVKRKRGR KKPLSGNHVQ PPETMKCNTF IRQVKEEHGR HT
NCBI	NP_001035533
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PHD finger protein 11, APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34, RP11-185C18.3
Available
Antigen Species	Human
Applications info	SDS-PAGE, Denatured
Concentration	1 mg/ml (determined by Bradford assay)
Description	PHD finger protein 11, also known as PHF11, is a regulator of TH1-type cytokine gene expression. The reduction in PHF11 expression seen with an AD-associated genotype could contribute to the strong TH2 responses that characterize many allergic individuals. PHF11 are associated with increased total serum IgE levels, asthma, and severe atopic dermatitis (AD) in children. Although PHF11 includes a plant homeodomain, a motif often found in transcriptional regulators, the function of PHF11 has not been investigated. Recombinant human PHF11 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Domain	1-331aa
Expression System	E.coli
Formulation	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Gene Category	Epigenomics (Transcription & Translation)
General References	Clarke E., et al. (2008) J. Allergy Clin. Immunol. 121:1148-1154 Scanlan M.J., et al. (1999) Int. J. Cancer. 83:456-464
Molecular Weight	39.7 kDa (351aa)
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 10/4/2024

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