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Recombinant human HIBCH protein

Recombinant human HIBCH protein

Item no.	NKM-ATGP1469-250ug
Manufacturer	NKMAX
Amount	250ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins By Organ Lung Cancer Thyroid Cancer
Type	Proteins Recombinant
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 90% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MGSHMDAAEE VLLEKKGCTG VITLNRPKFL NALTLNMIRQ IYPQLKKWEQ DPETFLIIIK GAGGKAFCAG GDIRVISEAE KAKQKIAPVF FREEYMLNNA VGSCQKPYVA LIHGITMGGG VGLSVHGQFR VATEKCLFAM PETAIGLFPD VGGGYFLPRL QGKLGYFLAL TGFRLKGRDV YRAGIATHFV DSEKLAMLEE DLLALKSPSK EN
NCBI	NP_055177
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	3-hydroxyisobutyryl-CoA hydrolase mitochondrial, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, HIBYLCOAH
Available
Antigen Species	Human
Applications info	SDS-PAGE
Concentration	1.0 mg/ml (determined by Bradford assay)
Description	HIBCH is the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants. Recombinant human HIBCH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Domain	33-386aa
Expression System	E.coli
Formulation	Liquid. 20mM Tris-HCl buffer (pH 8.0)containing 10% glycerol 0.2M NaCl, 1mM DTT
Gene Category	Signal Transduction
General References	Hendrickson, S.L. et al. (2010) PLoS ONE 5 (9), E12862 Wu, C. et al. (2007) Proteomics 7 (11), 1775-1785
Molecular Weight	42.1kDa(379aa), confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250ug

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Delivery expected until 8/30/2024

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