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Recombinant human PTRH2 protein

Recombinant human PTRH2 protein

Item no.	NKM-ATGP0830-500ug
Manufacturer	NKMAX
Amount	500ug
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Autophagy SDS-PAGE By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 95% by SDS-PAGE
NCBI	NP_057161
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PTRH2, Peptidyl-tRNA hydrolase 2, BIT1, PTH2, CGI-147, Bcl-2 inhibitor of transcription 1
Available
Antigen Species	Human
Concentration	1mg/ml (determined by Bradford assay)
Description	PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1, is a mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondria to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. The natural substrate for PTRH2 may be petidyl-tRNAs which drop off the ribosome during protein synthesis. Recombinant human PTRH2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Expression System	E.coli
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT
Gene Category	Apoptosis
General References	Jan Y., et al. (2004) Cell. 116(5):751-62.; ; De Pereda JM., et al. (2004) J Biol Chem. 279(9):8111-5.
Molecular Weight	14.9 kDa (137aa) confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500ug

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Delivery expected until 8/30/2024

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