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Recombinant human SEPSECS protein

Recombinant human SEPSECS protein

Item no.	NKM-ATGP0806-50ug
Manufacturer	NKMAX
Amount	50ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 90% by SDS-PAGE
NCBI	NP_058651
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	O-phosphoseryl-tRNA(Sec) selenium transferase, O-phosphoseryl-tRNA(Sec) selenium transferase
Available
Antigen Species	Human
Bioassay Procedure	MGSSHHHHHH SSGLVPRGSH MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD IEEMALKLDN VLLDTYQDAS S
Concentration	0.25mg/ml (determined by Bradford assay)
Description	SEPSECS, also known as SLA/LP autoantigen, catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA (sec) to selenocysteinyl-tRNA (sec) using selenophosphate as the selenium donor. Also, this protein is considered a specific marker of autoimmune hepatitis. Recombinant human SEPSECS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Domain	1-501aa
Expression System	E.coli
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 40% glycerol, 0.15M NaCl, 1mM DTT
Gene Category	Enzymes & Proteases
General References	Palioura S., et al. (2009) Science. 325(5938):321-5.; ; Yuan J., et al. (2006) Proc. Natl. Acad. Sci. u.S.A. 103:18923-18927
Molecular Weight	57.9 kDa (521aa) confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 10/4/2024

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