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Recombinant human IMPA1/IMP1 protein

Recombinant human IMPA1/IMP1 protein

Item no.	NKM-ATGP0737-100ug
Manufacturer	NKMAX
Amount	100ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 95% by SDS - PAGE
Sequence	MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMATP PKRSCPSFSA SSEGTRIKKI SIEGNIAAGK STFVNILKQL CEDWEVVPEP VARWCNVQST QDEFEELTMS QKNGGNVLQM MYEKPERWSF TFQTYACLSR IRAQLASLNG KLKDAEKPVL FFERSVYSDR YIFASNLYES ECMNETEWTI YQDWHDWMNN QFGQSLELDG IIYLQATPET CLHRIYLRGR NE
NCBI	NP_005527
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Inositol monophosphatase 1, IMPA, IMP, IMPase 1, Inositol monophosphatase 1
Available
Antigen Species	Human
Applications info	SDS-PAGE
Concentration	1 mg/ml (determined by Bradford assay)
Description	IMPA1 (inositol monophosphatase1) is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. It plays a key role in the phosphatidylinositol signaling pathway by catalyzing the hydrolysis of inositol monophosphates. This protein has been identified as the pharmacological target for lithium action in the brain. Recombinant human IMPA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Domain	1-277aa
Expression System	E.coli
Formulation	Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
Gene Category	Metabolism
General References	Schapiro MB., et al. (2002) Neurobiol Aging. 23(3):389-96. Atack JR., et al. (1992) Proc Natl Acad Sci u S A. 89(21):10031-5.
Molecular Weight	32.3 kDa(297aa), confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 10/4/2024

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