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Recombinant human CBFB protein

Recombinant human CBFB protein

Item no.	NKM-ATGP0667-100ug
Manufacturer	NKMAX
Amount	100ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 85% by SDS-PAGE
NCBI	NP_001746
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Core-binding factor beta subunit, PEBP2B (polyomavirus enhancer binding protein b), PEA2, CBF-beta, Core-binding factor, beta subunit
Available
Antigen Species	Human
Bioassay Procedure	MGSSHHHHHH SSGLVPRGSH MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIAFVAT GTNLSLQFFP ASWQGEQRQT PSREYVDLER EAGKVYLKAP MILNGVCVIW KGWIDLQRLD GMGCLEFDEE RAQQEDALAQ QAFEEARRRT REFEDRDRSH REEMEVRVSQ LLAVTGKKTT RP
Concentration	0.5mg/ml (determined by Bradford assay)
Description	CBFB, also known as PEBP2B, is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e. g., RuNX1) and osteogenesis (e. g., RuNX2). This protein is a non-DNA binding regulatory subunit and it allosterically enhances DNA binding by alpha subunit. Recombinant human CBFB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Domain	1-182aa
Expression System	E.coli
Formulation	Liquid in. 20mM MES buffer (pH 6.0) containing 0.1mM PMSF, 10% glycerol
Gene Category	Epigenomics (Transcription & Translation)
General References	Speck NA., et al. (2009) Blood. 113(13):3070-9.; ; Ito Y., et al. (2008) Blood. 112(9):3777-87.; ;
Molecular Weight	23.6 kDa (202aa) confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 8/30/2024

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