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Recombinant human Glutaredoxin 3/GLRX3 protein

Recombinant human Glutaredoxin 3/GLRX3 protein

Item no.	NKM-ATGP0551-0.5mg
Manufacturer	NKMAX
Amount	0.5mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 95% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGELI GG
NCBI	NP_006532
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2, GRX3, glutaredoxin 4, bA500G10.4, GLRX4, GRX4, thioredoxin-like 2, thioredoxin-like 2, glutaredoxin 3,
Available
Antigen Species	Human
Applications info	SDS-PAGE
Concentration	0.5 mg/ml (determined by Bradford assay)
Description	Glutaredoxin (GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Domain	1-335aa
Expression System	E.coli
Formulation	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
Gene Category	Redox Proteins
General References	Witte S., et al. (2000) J Biol Chem 275(3): 1902-9. Haunhorst P., et al. (2010) Biochem Biophys Res Commun. 394(2):372-6
Molecular Weight	39.6kDa (355aa), confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 10/4/2024

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