Comparison

Recombinant human NQO-1 protein

Item no. NKM-ATGP0392-500ug
Manufacturer NKMAX
Amount 500ug
Category
Type Proteins Recombinant
Applications SDS-PAGE
Specific against other
Conjugate/Tag His-Tag
Purity > 95% by SDS-PAGE
NCBI NP_000894
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NQO1,
Available
Antigen Species
Human
Concentration
1mg/ml (determined by Bradford assay)
Description
NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Recombinant NQO1 protein was expressed in E. coli and purified by using conventional chromatography techniques
Expression System
E.coli
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Gene Category
Redox Proteins
General References
Jaiswal AK., et al. (1988) J Biol Chem. 263(27):13572-8. ; ; Traver RD., et al. (1992) Cancer Res. 52(4):797-802.; ;
Molecular Weight
33.0 kDa (294aa) confirmed by MALDI-TOF
Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500ug
Available: In stock
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