Item no. |
NKM-ATGP0383-500ug |
Manufacturer |
NKMAX
|
Amount |
500ug |
Category |
|
Type |
Proteins Recombinant |
Applications |
SDS-PAGE |
Specific against |
other |
Conjugate/Tag |
Non-Tagged |
Purity |
> 95% by SDS-PAGE |
NCBI |
NP_000651 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
TGF-b1, Transforming growth factor beta 1, CED, DPD1, TGFB, Transforming growth factor beta 1, TGFB1, TGFbeta, Camurati-Engelmann disease, TGFb1 |
Available |
|
Antigen Species |
Human |
Concentration |
0.5mg/ml (determined by Bradford assay) |
Description |
Transforming growth factor beta 1 (TGF-beta1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. Many cells synthesize TGFb1 and almost all of them have specific receptors for it. It positively and negatively regulates many other growth factors. Also, TGF-beta1 plays an important role in bone remodeling, controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Recombinant TGF-beta1 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
Endotoxin |
< 1 EU per 1ug of protein (determined by LAL method) |
Expression System |
E.coli |
Formulation |
Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol |
Gene Category |
Hormones & Cytokines |
General References |
Lebman DA., et al. (1999) Microbes Infect. 1(15):1297-304.; ; Wahl SM., et al. (1988) J Immunol. 140(9):3026-32. ; ; |
Molecular Weight |
12.9 kDa (113aa) confirmed by MALDI-TOF |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.