Item no. |
MSP-RE102-500UG |
Manufacturer |
KactusBio
|
Amount |
500 ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Liquid |
Specific against |
Rat |
Host |
E.coli |
Conjugate/Tag |
HIS |
Purity |
> 95% as determined by Tris-Bis PAGE |
Formula |
Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl (pH 9.0). |
Dry ice |
Yes
|
Sequence |
Thr287-Phe685 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
MAP19; MASP-2; MASP1P1; sMap |
Available |
|
Description |
Recombinant Rat MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685. |
Background |
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19. |
Manufacturers Product Type |
Recombinant Protein |
Endotoxin |
Less than 1EU per μg by the LAL method. |
Molecular Weight |
The protein has a predicted MW of 46.7 kDa. Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result. |
Stability and Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl (pH 9.0). |
Tag Information |
C-His |
Formulation |
Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl (pH 9.0). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.