Item no. |
MIE-M82Q8-25ug |
Manufacturer |
ACROBiosystems
|
Amount |
25 ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Powder |
Specific against |
Mouse |
Host |
HEK293 |
Conjugate/Tag |
Biotin, HIS, Avi |
Purity |
95% |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
MDK,MEK,Midkine,MK1,MKARAP,NEGF2,Retinoic acid-induced differentiation factor |
Available |
|
Manufacturers Category |
Under_Development / MABSol® Biotin Labeled Proteins |
Description |
Biotinylated Mouse Midkine, His, Avitag (MIE-M82Q8) is expressed from human 293 cells (HEK293). It contains AA Lys 23 - Asp140 (Accession # P12025-1). |
Molecule |
Midkine |
Exp Region |
Lys 23 - Asp140 |
Storage |
-20℃ |
Shipping |
RT |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Molecular Weight |
16.8 kDa |
Characteristics |
This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 16.8 kDa. The protein migrates as 20-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
PBS, pH7.4 |
Background |
Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors.Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups.Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.