Comparison

Human Galectin-9 / LGALS9 Protein, His Tag European Partner

Item no. LG9-H5244-50ug
Manufacturer ACROBiosystems
Amount 50 ug
Quantity options 1 mg 50 ug
Category
Type Proteins Recombinant
Format Powder
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag HIS, Unconjugated
Purity 95%
Citations (1) Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422. (2) Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981.
NCBI BAA31542.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Galectin-9,LGALS9,Ecalectin
Shipping condition Room temperature
Available
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
N-6×His, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
36.6 kDa
Description
Human Galectin-9, His Tag (LG9-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2).
Background
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
Molecule
Galectin-9
Exp Region
Ala 2 - Thr 323
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
20 mM MOPS, 50 mM NaCl, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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