Item no. |
LG9-H5244-1mg |
Manufacturer |
ACROBiosystems
|
Amount |
1 mg |
Quantity options |
1 mg
50 ug
|
Category |
|
Type |
Proteins Recombinant |
Format |
Powder |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 |
Conjugate/Tag |
HIS, Unconjugated |
Purity |
95% |
Citations |
(1) Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422. (2) Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981. |
NCBI |
BAA31542.1 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Galectin-9,LGALS9,Ecalectin |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Category |
Protein / Immune Checkpoint Proteins |
Manufacturer - Conjugate / Tag |
N-6×His, Unconjugated |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
36.6 kDa |
Description |
Human Galectin-9, His Tag (LG9-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2). |
Background |
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth. |
Molecule |
Galectin-9 |
Exp Region |
Ala 2 - Thr 323 |
Characteristics |
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
20 mM MOPS, 50 mM NaCl, pH7.4 |
Stability |
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.