Comparison

Recombinant Human CNDP1 Protein, His Tag

Item no. KMD-KMH896-100ug
Manufacturer KMD Bioscience
Amount 100 ug
Category
Type Proteins Recombinant
Specific against Human
Host Mammalian cell
Conjugate/Tag His
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CN1, CPGL2, HsT2308, carnosine dipeptidase 1
Available
Molecular Name
CNDP1
Source
This protein contains the human CNDP1(Pro28-His507) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Uniprot Accession
Q96KN2
Purity
>=90% as determined by SDS-PAGE
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer
PBS
Purification
Protein A/G
Predicted Molecular Weight
52.91kDa
Background
CNDP1, also known as beta-Ala-His dipeptidase, belongs to the peptidase M2A family. The shortest allelic form (CNDP1 Mannheim) was more common in the absence of nephropathy and was associated with lower serum carnosinase levels. Carnosine inhibited the increased production of fibronectin and collagen type VI in podocytes and the increased production of TGF-beta in mesangial cells. Diabetic patients with the CNDP1 Mannheim variant are less susceptible for nephropathy. Carnosine protects against the adverse effects of high glucose levels on renal cells.
Storage
Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition
This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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