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Recombinant Human CD321/F11R Protein, His Tag

Recombinant Human CD321/F11R Protein, His Tag

Manufacturer	KMD Bioscience
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human
Amount	50 ug
Host	Mammalian cell
Item no.	KMD-KMH464-50ug
Targets	CD321
Conjugate/Tag	His
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1, F11 receptor
Molecular Name	F11R
Source	This protein contains the human F11R(Met1-Val238) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Uniprot Accession	Q9Y624
Purity	>=90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	26.62kDa
Background	As a typeItransmembrane receptor belonging to the immunoglobulin superfamily, the human JAM-A, also known as platelet adhesion molecule 1(PAM-1) and platelet F11 receptor, is the firstly identified member of the Junctional Adhesion Molecule (JAM) family comprising at least three members. JAM-A is specifically localized in tight junctions of epithelial and endothelial cells and is involved in the regulation of junctional integrity and permeability by serving as a physical barrier in a homophilic manner. JAM-A is also expressed on the surface of hematopoeitic cells, such as platelets and leukocytes, and acts as a ligand for integrin LFA-1 or a platelet receptor, consequently plays key roles in a variety of cellular processes, including platelet aggregation, leukocyte transmigration, and angiogenesis. In addition, JAM-A has also been implicated in the attachment of reovirus that causes diarrhea in human.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 8/16/2024

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