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Human KLRG1 Protein, His Tag

Human KLRG1 Protein, His Tag

Item no.	KL1-H5249-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Amino Acids
Type	Proteins
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	HIS, Unconjugated
Purity	90%
NCBI	NP_001316028.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KLRG1
Shipping condition	Room temperature
Available
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	N-10×His, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	17.4 kDa
Description	Human KLRG1, His Tag (KL1-H5249) is expressed from human 293 cells (HEK293). It contains AA Leu 60 - Phe 195 (Accession # Q96E93-1).
Background	The co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1) is specifically expressed on NK cells and activated CD8+ T-cells and has been postulated to be a marker of senescence. KLRG1+ T cells are a major reason of chronic tissue damage in some autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. In tumors, tumor cells which express E-cadherin or N-cadherin bind to KLRG1 and inhibit the antitumor activity of T and NK cells. Thus, KLRG1 acts as an immunocheckpoint inhibitory receptor.
Molecule	KLRG1
Exp Region	Leu 60 - Phe 195
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.4 kDa. The protein migrates as 30-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

KL1-H5249-100ug-datasheet.pdf

KL1-H5249-100ug-safety-datasheet.pdf