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PE-Labeled Human IL-15 R alpha / CD215 Protein, Fc Tag (Site-specific conjugation) European Partner

Item no. ILA-HP2F6-200tests
Manufacturer ACROBiosystems
Amount 200 tests
Quantity options 200 tests 25 tests
Category
Type Proteins
Format Powder
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Fc, PE
NCBI NP_002180.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-15 R alpha,CD215,IL15RA,IL-15RA,IL-15R-alpha
Shipping condition Room temperature
Available
Manufacturer - Category
Protein / Fluorescent labeled protein
Manufacturer - Conjugate / Tag
C-Fc, PE Labeled
Shipping Temperature
RT
Storage Conditions
-20°C, aviod light
Molecular Weight
46.6 kDa
Description
PE-Labeled Human IL-15 R alpha / CD215 Protein, Fc Tag (Cat. No.ILA-HP2F6) is produced via site-specific conjugation of PE to Human IL-15 R alpha / CD215 Protein, Fc Tag under optimal conditions with a proprietary technology. PE-Labeled Human IL-15 R alpha, Fc Tag (ILA-HP2F6) is expressed from human 293 cells (HEK293). It contains AA Ile 31 - Thr 205 (Accession # Q13261-1).
Background
IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
Molecule
IL-15 R alpha
Exp Region
Ile 31 - Thr 205
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.6 kDa.
Buffer
PBS, 0.5% BSA, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 tests
Available: In stock
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