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Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) (IL8-CM1BPB)

Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) (IL8-CM1BPB)

Item no.	IL8-CM1BPB-100UG
Manufacturer	KactusBio
Amount	100 ug
Quantity options	100 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Monkey
Host	HEK293
Conjugate/Tag	HIS
Purity	> 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC
Formula	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Dry ice	Yes
Sequence	Thr28-Pro207
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Specificity	Cynomolgus
Manufacturer - Product Type	Recombinant Protein
Description	Recombinant Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr28-Pro207.
Background	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer, components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
Endotoxin	Less than 1 EU per μg by the LAL method.
Molecular Weight	The protein has a predicted MW of 21.14 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Target	IL-18BP
Manufacturer - Tag	C-His
Stability and Storage	Valid for 12 months from date of receipt when stored at -80°C; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Biotinylated	yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

IL8-CM1BPB-100UG-datasheet.pdf

IL8-CM1BPB-100UG-safety-datasheet.pdf