« Back
Home /
Rabbit IL-5 Protein, His Tag

Rabbit IL-5 Protein, His Tag

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Rabbit
Format	Powder
Amount	1 mg
Host	HEK293
Item no.	IL5-R52H4-1mg
Conjugate/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Purity	90%
Manufacturers Category	Protein / Cytokines&Growth Factors
Description	Rabbit IL-5, His Tag (IL5-R52H4) is expressed from human 293 cells (HEK293). It contains AA Met 20 - Ser 134 (Accession # G1SL79-1).
Molecule	IL-5
Exp Region	Met 20 - Ser 134
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	15.2 kDa
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 15.2 kDa. The protein migrates as 15 kDa and 16-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease. Drugs that target IL-5 are mepolizumab and reslizumab.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mg

available

Delivery expected until 7/26/2024

Express Delivery: Save 2 days

Compare

Add to wishlist

Recommend by mail