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Human IL-22 R alpha 1 Protein, Fc Tag

Human IL-22 R alpha 1 Protein, Fc Tag

Item no.	IL1-H5258-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Amino Acids
Type	Proteins
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	95%
NCBI	NP_067081.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-22 receptor subunit alpha-1,IL-22 receptor subunit alpha-1,IL-22R-alpha-1,IL-22RA1,Cytokine receptor class-II member 9,Cytokine receptor family 2 member 9,CRF2-9,ZcytoR11,IL22RA1 ,IL22R
Shipping condition	Room temperature
Available
Manufacturer - Category	Protein / Cytokines&Growth Factors
Manufacturer - Conjugate / Tag	Unconjugated, C-Fc
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	50.9 kDa
Description	Human IL-22 R alpha 1, Fc Tag (IL1-H5258) is expressed from human 293 cells (HEK293). It contains AA His 16 - Thr 228 (Accession # Q8N6P7-1).
Background	Interleukin-22 receptor subunit alpha-1(IL22RA1) is a component of the receptor for IL20, IL22 and IL24.Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Molecule	IL-22 R alpha 1
Exp Region	His 16 - Thr 228
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.9 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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IL1-H5258-1mg-datasheet.pdf

IL1-H5258-1mg-safety-datasheet.pdf