Item no. |
IFN-MM4R1-100UG |
Manufacturer |
KactusBio
|
Amount |
100 ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized |
Specific against |
Mouse |
Host |
HEK293 |
Conjugate/Tag |
Avi, HIS |
Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Formula |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Sequence |
Glu27-Thr429 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC |
Available |
|
Description |
Recombinant Mouse IFN alpha/beta R1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu27-Thr429. |
Background |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. |
Manufacturers Product Type |
Recombinant Protein |
Endotoxin |
Less than 1EU per μg by the LAL method. |
Molecular Weight |
The protein has a predicted MW of 46.9 kDa. Due to glycosylation, the protein migrates to 67-70 kDa based on Tris-Bis PAGE result. |
Stability and Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3-6 months after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Tag Information |
C-His-Avi |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.