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DcR3/TNFRSF6B, Human (sf9, hFc)

DcR3/TNFRSF6B, Human (sf9, hFc)

Item no.	HY-P75306-10ug
Manufacturer	MedChem Express
Amount	10 ug
Quantity options	100 ug 10 ug 200 ug 2 ug 50 ug 5 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	95.80
Dry ice	Yes
Citations	[1]Zhan C, et al. Decoy strategies: the structure of TL1A:DcR3 complex. Structure. 2011 Feb 9;19(2):162-71.<br/>[2]Lagou S, et al. The Role of Decoy Receptor DcR3 in Gastrointestinal Malignancy. Cancer Diagn Progn. 2022 Jul 3;2(4):411-421.<br/>[3]Ge H, et al. DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway. Onco Targets Ther. 2018 Jul 19;11:4177-4187.<br/>[4]Liu YP, et al. DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC. Oncotarget. 2016 Nov 22;7(47):77306-77318.<br/>[5]Gao L, et al. DcR3, a new biomarker for sepsis, correlates with infection severity and procalcitonin. Oncotarget. 2017 Dec 28;9(13):10934-10944.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DcR3/TNFRSF6B Protein, Human (sf9, hFc),Human,Sf9 insect cells
Available
Product Description	DcR3 is a secreted member of the Tumor Necrosis Factor (TNF) receptor superfamily, recognized as a significant anti-apoptotic factor with prominent involvement in various inflammatory and neoplastic conditions. DcR3 can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL against apoptosis[1][2][3]. DcR3 has been associated with tumorigenesis and metastasis, via DcR3/STAT1/IRF1 feedback loop[4][5]. DcR3/TNFRSF6B Protein, Human (sf9, hFc) has a full length of 300 amino acids (M1-H300), produced in sf9 insect cells with C-terminal hFc-tag.
StorageTemperature	Stored at -80°C for 1 year
Shipping	Dry Ice
MolecularWeight	Approximately 65 kDa
Manufacturers Product type	Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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