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GITR, Human (T45A, HEK293, mFc)

GITR, Human (T45A, HEK293, mFc)

Item no.	HY-P70822-50ug
Manufacturer	MedChem Express
Amount	50 ug
Quantity options	10 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Cytokine
Specific against	other
Purity	95.0
Citations	[1]Tian J, et al. The Role of GITR/GITRL Interaction in Autoimmune Diseases. Front Immunol. 2020 Oct 9;11:588682.<br>[2]Krausz LT, et al. GITR-GITRL system, a novel player in shock and inflammation. ScientificWorldJournal. 2007 May 1;7:533-66.<br>[3]Shin HH, et al. Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage. FEBS Lett. 2002 Mar 13;514(2-3):275-80.<br>[4]Liu Y, et al. Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma. PLoS One. 2013 Jun 13;8(6):e66982.
Smiles	QRPTGGPGCG PGRLLLGTGA DARCCRVHTT RCCRDYPGEE CCSEWDCMCV QPEFHCGDPC CTTCRHHPCP PGQGVQSQGK FSFGFQCIDC ASGTFSGGHE GHCKPWTDCT QFGFLTVFPG NKTHNAVCVP GSPPAE
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	GITR Protein, Human (T45A, HEK293, mFc),Human,HEK293
Available
Product Description	GITR (TNFRSF18) is a member of the TNFR superfamily. GITR promotes T cell activation and proliferation and increases resistance to tumors and viral infections, and exacerbates autoimmune diseases and inflammation processes[1]. GITR Protein, Human (T45A, HEK293, mFc) is a recombinant protein with a C-terminal Fc label and T at position 45 is mutated to A. It consists of 136 amino acids (Q26-E161) and is produced in HEK293 cells.
StorageTemperature	Stored at -20°C for 2 years
Shipping	Blue Ice
MolecularWeight	40-55 kDa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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