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Cynomolgus HPX Protein (HPX-CM101)

Cynomolgus HPX Protein (HPX-CM101)

Item no.	HPX-CM101-500UG
Manufacturer	KactusBio
Amount	500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized
Specific against	Monkey
Host	HEK293
Conjugate/Tag	HIS
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Formula	Lyophilized from 0.22μm filtered solution in 20mM MES, 150mM NaCl (pH 6.0). Normally 8% trehalose is added as protectant before lyophilization.
Sequence	Asn24-Tyr462
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Recombinant Cynomolgus HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn24-Tyr462.
Background	Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.
Manufacturers Product Type	Recombinant Protein
Endotoxin	Less than 1EU per μg by the LAL method.
Molecular Weight	The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.
Stability and Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3-6 months after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22μm filtered solution in 20mM MES, 150mM NaCl (pH 6.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 20mM MES, 150mM NaCl (pH 6.0).
Tag Information	C-His
Formulation	Lyophilized from 0.22μm filtered solution in 20mM MES, 150mM NaCl (pH 6.0). Normally 8% trehalose is added as protectant before lyophilization.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

HPX-CM101-500UG-datasheet.pdf

HPX-CM101-500UG-safety-datasheet.pdf