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Human HGF Protein, Fc Tag (MALS verified)

Human HGF Protein, Fc Tag (MALS verified)

Item no.	HGF-H5253-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	90%
Citations	(1) Johnson M, et al. Hepatology. 1993. 17(6):1052-61. (2) Bottaro DP, et al. Science. 1991. 251(4995):802-4. (3) Stamos J, et al. EMBO J. 2004. 23(12):2325-35.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	HGF,HPTA,SF
Available
Manufacturers Category	Protein / Cytokines&Growth Factors
Description	Human HGF, Fc Tag (HGF-H5253) is expressed from human 293 cells (HEK293). It contains AA Gln 32 - Ser 728 (Accession # P14210-1).
Molecule	HGF
Exp Region	Gln 32 - Ser 728
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	106.1 kDa
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 106.1 kDa. The protein migrates as 105-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Background	Hepatocyte growth factor (HGF) is a paracrine cellular growth, motility and morphogenic factor. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. In addition, HGF has been implicated in a variety of cancers, including of the lungs, pancreas, thyroid, colon, and breast.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 9/20/2024

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