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Mouse FGL1 Protein, Fc Tag European Partner

Item no. FG1-M5258-1mg
Manufacturer ACROBiosystems
Amount 1 mg
Category
Type Proteins Recombinant
Format Powder
Specific against Mouse
Host HEK293
Conjugate/Tag Unconjugated, Fc
Purity 95%
Citations (1) Nagdas SK. 2016. Int J Biochem Cell Biol. 80:163-172. (2) Jin H. 2018 Nov 7. J Mol Med (Berl). (3) Zhang Y. 2018 Aug. Mol Med Rep. 18(2):1465-1472.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FGL1,Hepassocin,HP-041,HFREP-1,LFIRE-1,HFREP1
Available
Manufacturers Category
Protein / Bio-Markers & CD Antigens
Description
Mouse FGL1, Fc Tag (FG1-M5258) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Ile 314 (Accession # Q71KU9-1).
Molecule
FGL1
Exp Region
Leu 23 - Ile 314
Storage
-20℃
Shipping
RT
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight
60.5 kDa
Characteristics
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
Background
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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