Item no. |
FG1-M5258-1mg |
Manufacturer |
ACROBiosystems
|
Amount |
1 mg |
Category |
|
Type |
Proteins Recombinant |
Format |
Powder |
Specific against |
Mouse |
Host |
HEK293 |
Conjugate/Tag |
Unconjugated, Fc |
Purity |
95% |
Citations |
(1) Nagdas SK. 2016. Int J Biochem Cell Biol. 80:163-172. (2) Jin H. 2018 Nov 7. J Mol Med (Berl). (3) Zhang Y. 2018 Aug. Mol Med Rep. 18(2):1465-1472. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
FGL1,Hepassocin,HP-041,HFREP-1,LFIRE-1,HFREP1 |
Available |
|
Manufacturers Category |
Protein / Bio-Markers & CD Antigens |
Description |
Mouse FGL1, Fc Tag (FG1-M5258) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Ile 314 (Accession # Q71KU9-1). |
Molecule |
FGL1 |
Exp Region |
Leu 23 - Ile 314 |
Storage |
-20℃ |
Shipping |
RT |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Molecular Weight |
60.5 kDa |
Characteristics |
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
Tris with Glycine, Arginine and NaCl, pH7.5 |
Background |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis. |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.