Comparison

Mouse BTLA Protein, His Tag

Item no. DIM-PME100526-10ug
Manufacturer DIMA Biotechnology
Amount 10 ug
Category
Type Proteins Recombinant
Format Lyophilized
Specific against Mouse
Host HEK293
Conjugate/Tag His
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BTLA,CD272
Available
Name
Mouse BTLA
Purity
> 95%
Purification
affinity purification
Conjugate
C-6xHis tag
Storage
Store at -80C for 12 months (Avoid repeated freezing and thawing)
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution
Reconstitute with deionized water
Sequence
Mouse BTLA(Glu30-Pro176) +6xHis tag
Description
Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).
Gene ID
208154
Swiss-Prot
Q7TSA3
Molecular Weight
35-55 kDa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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