Recombinant Human NADPH--cytochrome P450 reductase(POR),partial

Signal Transduction

Not Test

Homo sapiens (Human)

INMGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSL IVGLLTYWFLFRKKKEEVPEFTKIQTLTSSVRESS FVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAH RYGMRGMSADPEEYDLADLSSLPEIDNALVVFCMA TYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGL GNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDD DGNLEEDFITWREQFWLAVCEHFGVEATGEESSIR QYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDA KNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIR YESGDHVAVYPANDSALVNQLGKILGADLDVVMSL NNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRT NVLYELAQYASEPSEQELLRKMASSSGEGKELYLS WVVEARRHILAILQDCPSLRPPIDHLCELLPRLQA RYYSIASSSKVHPNSVHICAVVVEYETKAGRINKG VATNWLRAKEPVGENGGRALVPMFVRKSQFRLPFK ATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVG ETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNV AFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYV CGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIK KLMTK

2-671aa

102.9 kDa

Polymorphism of human CYPOR expression of new allele.Czerwinski M., Sahni M., Madan A., Parkinson A. cDNA cloning and characterization of NADPH-cytochrome P-450 reductase in human HL-60 cell.Murakami H.O., Ogawa H., Nisimoto Y.NIEHS SNPs programThe DNA sequence of human chromosome 7.Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.Nature 424:157-164(2003)

Liquid or Lyophilized powder

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.

Antley-Bixler syndrome, with genital anomalies and disordered steroidogenesis (ABS1); Disordered steroidogenesis due to cytochrome P450 oxidoreductase deficiency (DISPORD)

NADPH--cytochrome P450 reductase family; Flavodoxin family; Flavoprotein pyridine nucleotide cytochrome reductase family