Item no. |
CLE-HM22A-100UG |
Manufacturer |
KactusBio
|
Amount |
100 ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized |
Specific against |
Human |
Host |
HEK293 |
Conjugate/Tag |
N-hFc |
Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Sequence |
His65-Ala265 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2 |
Available |
|
Description |
Recombinant Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains His65-Ala265. |
Background |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. |
Manufacturers Product Type |
Recombinant Protein |
Endotoxin |
Less than 1EU per μg by the LAL method. |
Molecular Weight |
The protein has a predicted MW of 50.9 kDa. Due to glycosylation, the protein migrates to 68-73 kDa based on Tris-Bis PAGE result. |
Stability and Storage |
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.