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Rhesus macaque CDH17/Cadherin 17 Protein (CDH-RM117)

Rhesus macaque CDH17/Cadherin 17 Protein (CDH-RM117)

Manufacturer	KactusBio
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Rhesus macaque
Format	Lyophilized
Amount	500 ug
Host	HEK293
Item no.	CDH-RM117-500UG
Targets	CDH17/Cadherin 17
Conjugate/Tag	HIS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Description	Recombinant Rhesus macaque CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Thr784.
Background	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Manufacturers Product Type	Recombinant Protein
Endotoxin	Less than 1EU per μg by the LAL method.
Molecular Weight	The protein has a predicted MW of 85.60 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
Stability and Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3-6 months after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag Information	C-His
Formulation	Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CDH-RM117-500UG-datasheet.pdf

CDH-RM117-500UG-safety-datasheet.pdf