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Cynomolgus CD3 epsilon&CD3 delta Heterodimer Protein, Fc,His Tag&Fc,Flag Tag (MALS verified)

Cynomolgus CD3 epsilon&CD3 delta Heterodimer Protein, Fc,His Tag&Fc,Flag Tag (MALS verified)

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Monkey
Format	Powder
Amount	100 ug
Host	HEK293
Item no.	CDD-C52W9-100ug
Conjugate/Tag	Unconjugated, FLAG, HIS, Fc
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	CD3E & CD3D,CD3 delta & CD3 epsilon,CD3 delta / epsilon
Purity	90%
Manufacturers Category	Protein / Bio-Markers & CD Antigens
Description	Cynomolgus CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (CDD-C52W9) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asp 117 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # Q95LI5-1 (CD3E) & Q95LI8-1 (CD3D)).
Molecule	CD3E & CD3D
Exp Region	Gln 22 - Asp 117 (CD3E) & Phe 22 - Ala 105 (CD3D)
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	42.5 kDa (CD3E) & 40.9 kDa (CD3D)
Characteristics	Cynomolgus CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag is produced by co-expression of CD3E and CD3D, has a calculated MW of 42.5 kDa (CD3E) and 40.9 kDa (CD3D). Subunit CD3E is fused with a human IgG1 Fc tag and a polyhistidine tag at the C-terminus and subunit CD3D is fused with a human IgG1 Fc tag and a flag tag at the C-terminus. The predicted N-terminus is Gln 22 (CD3E) & Phe 22 (CD3D). The reducing (R) protein migrates as 46-50 kDa and 55-65 kDa due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/26/2024

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