Comparison

Mouse CD28 Protein, Fc Tag European Partner

Manufacturer ACROBiosystems
Category
Type Proteins Recombinant
Specific against Mouse
Format Powder
Amount 100 ug
Item no. CD8-M5257-100ug
Conjugate/Tag Fc
eClass 6.1 34160400
eClass 9.0 42020190
Available
Alias CD28,Tp44
Purity >90% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.7 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description
T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Endotoxin Level
Less than 1.0 EU per ug by the LAL method.
Exp Region
Asn 20 - Lys 149
Expression System
HEK293
Molecular Weight
41.7 kDa
Molecule
CD28
Shipping Conditions
RT
Storage
-20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: Out of stock
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