Comparison

Human CD8 alpha/CD8A Protein (CD8-HM18A)

Item no. CD8-HM18A-500UG
Manufacturer KactusBio
Amount 500 ug
Category
Type Proteins Recombinant
Format Lyophilized
Specific against Human
Host HEK293
Conjugate/Tag HIS
Purity > 95% as determined by Tris-Bis PAGE
Formula Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Sequence Ser22-Asp182
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Description
Recombinant Human CD8 alpha/CD8A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-Asp182.
Background
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Manufacturers Product Type
Recombinant Protein
Endotoxin
Less than 1EU per μg by the LAL method.
Molecular Weight
The protein has a predicted MW of 18.70 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Tris-Bis PAGE result.
Stability and Storage
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag Information
C-His
Formulation
Supplied as 0.22μm filtered solution in PBS (pH 7.4).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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